Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121303 | 1.00 | KMO (0.39) | KMORORCS1PR1S1PR3BTK | |
| SCHEMBL28828673 | 0.90 | KMO (0.40) | KMORORCS1PR1S1PR3BTK | |
| SCHEMBL27210440 | 0.90 | KMO (0.40) | KMORORCS1PR1S1PR3BTK | |
| SCHEMBL29228281 | 0.89 | PTGS2 (0.38) | KMOS1PR1MEN1LMNAKMT2A | |
| SCHEMBL29121317 | 0.88 | NR3C1 (0.37) | S1PR1 | |
| SCHEMBL27200876 | 0.88 | NR3C1 (0.37) | S1PR1 | |
| SCHEMBL29121310 | 0.87 | FFAR4 (0.40) | KMORORCS1PR1S1PR3BTK | |
| SCHEMBL29228228 | 0.86 | SLC6A3 (0.36) | — | |
| SCHEMBL29228388 | 0.86 | ERN1 (0.38) | RORCS1PR1MEN1LMNAKMT2A | |
| SCHEMBL29121296 | 0.85 | S1PR1 (0.38) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746422-B | Derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | claimed |
| CN-114746422-A | Novel derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2022-07-12 | — | — | CN | claimed |
| EP-4041734-B1 | DERIVATIVES HAVING 1,2,3,4-TETRAHYDRONAPHTHALENE MOIETY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORP (KR) | 2024-04-24 | — | — | EP | disclosed |
| CN-114746422-B | Derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | disclosed |
| CN-114746422-A | Novel derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2022-07-12 | — | — | CN | disclosed |