SCHEMBL28828677

SCHEMBL28828677

CN(C)c1cc(-c2ccc3c(c2)CC(C)(C)C3OC(N)=O)ccc1F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 1/20 0.33
F2R P25116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28828604 0.88 CYP17A1 (0.33) F2R
SCHEMBL28828529 0.86 PDE4A (0.35) F2R
SCHEMBL28828388 0.85 DAPK3 (0.38) F2R
SCHEMBL28828601 0.84 TDP2 (0.39)
SCHEMBL28828422 0.84 HDAC6 (0.36)
SCHEMBL28828426 0.84 KDM1A (0.39) F2R
SCHEMBL28828667 0.83 SLC6A3 (0.37) F2R
SCHEMBL28828556 0.83 F2R (0.35) F2R
SCHEMBL28828686 0.82 SIRT1 (0.36)
SCHEMBL28828591 0.82 F2R (0.42) F2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114829361-B Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same 柳韩洋行 2024-07-16 CN claimed
CN-114829361-A Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same 柳韩洋行 2022-07-29 CN claimed
CN-114829361-B Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same 柳韩洋行 2024-07-16 CN disclosed
CN-114829361-A Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same 柳韩洋行 2022-07-29 CN disclosed