Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829055 | 0.87 | GRIN1 (0.38) | GRIN1GRIN2BAVPR2AVPR1AHDAC2 | |
| SCHEMBL28828864 | 0.87 | GRIN1 (0.41) | GRIN1GRIN2BAVPR2AVPR1AMAPT | |
| SCHEMBL28828984 | 0.83 | APEX1 (0.46) | GRIN1GRIN2B | |
| SCHEMBL28828770 | 0.77 | AVPR2 (0.42) | AVPR2AVPR1A | |
| SCHEMBL28828769 | 0.77 | AVPR2 (0.42) | AVPR2AVPR1A | |
| SCHEMBL28829027 | 0.77 | ALDH1A1 (0.42) | GRIN1GRIN2BAVPR2AVPR1AHDAC2 | |
| SCHEMBL28828908 | 0.76 | TSHR (0.50) | LMNAHTTMAPT | |
| SCHEMBL168320 | 0.76 | APOBEC3G (0.45) | GRIN1GRIN2BAVPR2AVPR1AHDAC2 | |
| SCHEMBL28828841 | 0.69 | AKR1B10 (0.44) | GRIN1GRIN2B | |
| SCHEMBL28828872 | 0.69 | POLB (0.44) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835688-A | Substituted 4-aryl imidazole-2-ketone derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-02 | — | — | CN | disclosed |