SCHEMBL28829987

SCHEMBL28829987

FC(F)(F)c1ccc(OBOc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ALDH1A1 P00352 1/20 0.52
KIF11 P52732 1/20 0.50
SLC6A4 P31645 4/20 0.42
SLC6A2 P23975 3/20 0.42
SLC6A3 Q01959 3/20 0.42
KCNK2 O95069 2/20 0.42
KCNH2 Q12809 2/20 0.42
CACNA1C Q13936 2/20 0.42
TRPV6 Q9H1D0 1/20 0.42
MAPK14 Q16539 1/20 0.42
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
SLC7A5 Q01650 3/20 0.40
HRH3 Q9Y5N1 2/20 0.40
NPC1 O15118 2/20 0.40
CYP2D6 P10635 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204711 0.91 CA1 (0.47) TSHRALDH1A1KIF11TRPV6CA1
SCHEMBL254896 0.80 TSHR (0.59) TSHRALDH1A1KIF11SLC6A4SLC6A2
SCHEMBL8885 0.79 LTA4H (0.50) TSHRALDH1A1CA1CA2CA9
Hydrochloric Acid SCHEMBL693111 0.77 LTA4H (0.47) TSHRALDH1A1CA1CA2CA9
SCHEMBL3318479 0.76 LTA4H (0.40) TSHRALDH1A1SLC6A4PPARGPPARA
SCHEMBL289310 0.75 TSHR (0.47) TSHRALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL449851 0.75 LTA4H (0.63) TSHRCA1CA2CA9NPC1
SCHEMBL1658934 0.74 TSHR (0.36) TSHRALDH1A1RAB9AALOX15LTA4H
SCHEMBL4293490 0.74 MAOB (0.32) CA1CA2CA9
SCHEMBL820257 0.74 KIF11 (0.44) TSHRALDH1A1KIF11TRPV6CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114981249-A Benzopyrrole derivative and organic electroluminescent element comprising same 株式会社乐普拓 2022-08-30 CN disclosed