Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL28323390 | 0.86 | TSHR (0.42) | KIF11TRPV6ALDH1A1TSHR | |
| SCHEMBL204711 | 0.81 | CA1 (0.47) | KIF11CA1CA2CA9CES2 | |
| SCHEMBL14477632 | 0.80 | MEN1 (0.33) | CA1CA2CA9 | |
| SCHEMBL819920 | 0.79 | MAPT (0.48) | CA1CA2CA9ALDH1A1MAOB | |
| SCHEMBL5541013 | 0.77 | MAPT (0.47) | ALDH1A1MAOBAOC3TRPV1TSHR | |
| SCHEMBL4457498 | 0.77 | CES2 (0.41) | CES2 | |
| SCHEMBL28302381 | 0.77 | KIF11 (0.55) | KIF11CES2CES1ORAI1ORAI2 | |
| SCHEMBL121487 | 0.75 | KDM4E (0.46) | CES2MGLLMAOBAOC3TSHR | |
| SCHEMBL28829987 | 0.74 | TSHR (0.52) | KIF11CA1CA2CA9TRPV6 | |
| SCHEMBL16578067 | 0.73 | KIF11 (0.48) | KIF11CA1CA2CA9CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024536-B2 | C-terminal HSP90 inhibitors | UNIVERSITY OF KANSAS (US) | 2024-07-02 | — | — | US | disclosed |
| US-11858952-B2 | Compound and color conversion film comprising same | LG CHEM, LTD. (KR) | 2024-01-02 | — | — | US | disclosed |
| US-20230279016-A1 | Tetrahydropyrazolopyrimidines and Related Analogs for Inhibiting YAP/TAZ-TEAD | CISTIM LEUVEN VZW (BE) | 2023-09-07 | — | — | US | disclosed |
| EP-3013840-B1 | ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, DISPLAY ELEMENT, AND DIMMING ELEMENT | RICOH CO LTD (JP) | 2021-07-28 | — | — | EP | disclosed |
| US-10030041-B2 | C-terminal Hsp90 inhibitors | UNIVERSITY OF KANSAS (US) | 2018-07-24 | — | — | US | disclosed |
| US-20180086775-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2018-03-29 | — | — | US | disclosed |
| US-20180051021-A1 | BICYCLIC KETONE SULFONAMIDE COMPOUNDS | AMGEN INC. (US) | 2018-02-22 | — | — | US | disclosed |
| US-9856241-B2 | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | Karyopharm Therapeutics Inc. (US) | 2018-01-02 | — | — | US | disclosed |
| US-9792944-B2 | Recording material and optical information recording medium | FUJIFILM CORPORATION (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20170282170-A9 | PHOSPHORUS-CONTAINING CATALYSTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-10-05 | — | — | US | disclosed |
| WO-2014208775-A1 | ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, DISPLAY ELEMENT, AND DIMMING ELEMENT | RICOH COMPANY, LTD. (JP) | 2014-12-31 | — | — | WO | disclosed |
| US-8748015-B2 | Indenofluorenedione derivative, material for organic electroluminescent element, and organic electroluminescent element | IDEMITSU KOSAN CO., LTD. (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20140058106-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2014-02-27 | — | — | US | disclosed |
| US-8361959-B2 | Spiro-imidazolone derivatives as glucagon receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20130012434-A1 | NOVEL SPIRO IMIDAZOLONES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE | MERCK SHARP & DOHME CORP. | 2013-01-10 | — | — | US | disclosed |
| US-8183793-B2 | Method for synthesizing anthracene derivative and anthracene derivative, light emitting element, light emitting device, electronic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-05-22 | — | — | US | disclosed |
| US-20110284827-A1 | INDENOFLUORENEDIONE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| US-20110084230-A1 | Process for Synthesizing Organoelemental Compounds | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2011-04-14 | — | — | US | disclosed |
| US-20110054175-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2011-03-03 | — | — | US | disclosed |
| US-20110050118-A1 | METHOD FOR SYNTHESIZING ANTHRACENE DERIVATIVE AND ANTHRACENE DERIVATIVE, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, ELECTRONIC DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140058106-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PFAS, ODC1, AOC1 | KIF11 650/4885CA1 1711/4885CA2 3526/4885 |
| US-20110050118-A1 | METHOD FOR SYNTHESIZING ANTHRACENE DERIVATIVE AND ANTHRACENE DERIVATIVE, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, ELECTRONIC DEVICE | ALAD, CYP2C9, CYP1A1 | KIF11 4444/4885CA1 1625/4885CA2 1599/4885 |
| US-20170282170-A9 | PHOSPHORUS-CONTAINING CATALYSTS | AR, NR2C2, ORC3 | KIF11 4467/4885CA1 1490/4885CA2 447/4885 |
| US-20110284827-A1 | INDENOFLUORENEDIONE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT | HSD17B11, HSD17B2, HSD17B1 | KIF11 1128/4885CA1 2026/4885CA2 2773/4885 |
| US-20180051021-A1 | BICYCLIC KETONE SULFONAMIDE COMPOUNDS | TRPV1, TRPA1, KCNJ11 | KIF11 1449/4885CA1 1692/4885CA2 356/4885 |
| US-20130012434-A1 | NOVEL SPIRO IMIDAZOLONES AS GLUCAGON RECEPTOR ANTAGONISTS, COMPOSITIONS, AND METHODS FOR THEIR USE | GLP1R, GCGR, GIPR | KIF11 4328/4885CA1 4002/4885CA2 2119/4885 |
| US-20230279016-A1 | Tetrahydropyrazolopyrimidines and Related Analogs for Inhibiting YAP/TAZ-TEAD | YAP1, TEAD2, TEAD1 | KIF11 4106/4885CA1 4872/4885CA2 4538/4885 |
| US-20110084230-A1 | Process for Synthesizing Organoelemental Compounds | CHRM1, CHRM2, MLX | KIF11 2661/4885CA1 22/4885CA2 396/4885 |
| US-11858952-B2 | Compound and color conversion film comprising same | BLVRB, CDYL, CRY1 | KIF11 3482/4885CA1 2367/4885CA2 4342/4885 |
| US-10030041-B2 | C-terminal Hsp90 inhibitors | HSP90AB2P, HSP90AB1, HSP90B1 | KIF11 3823/4885CA1 4526/4885CA2 4338/4885 |
| US-12024536-B2 | C-terminal HSP90 inhibitors | HSP90AB2P, HSP90AB1, HSP90B1 | KIF11 3823/4885CA1 4526/4885CA2 4338/4885 |
| US-20110054175-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PFAS, ODC1, AOC1 | KIF11 650/4885CA1 1711/4885CA2 3526/4885 |
| US-20180086775-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | CRY1, CRY2, PPOX | KIF11 2976/4885CA1 4150/4885CA2 4509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.