Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950716 | 0.88 | ALDH1A1 (0.33) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL9460795 | 0.82 | CYP1A2 (0.39) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL6161512 | 0.82 | NPC1 (0.33) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL3559261 | 0.81 | ALDH1A1 (0.34) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL6163116 | 0.77 | NR1I2 (0.40) | ALDH1A1HSD17B10CYP1A2HPGDGAA | |
| SCHEMBL7951415 | 0.73 | CA2 (0.38) | ALDH1A1TSHRTDP1KIF11 | |
| SCHEMBL2885158 | 0.72 | CYP1A2 (0.45) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL6171086 | 0.72 | KIF11 (0.40) | KIF11 | |
| SCHEMBL5305428 | 0.69 | CYP1A2 (0.37) | ALDH1A1HSD17B10HIF1ACYP1A2HPGD | |
| SCHEMBL21812138 | 0.68 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847126-B2 | prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example | LANXESS DEUTSCHLAND GMBH (DE) | 2010-12-07 | — | — | US | disclosed |
| US-20070299273-A1 | prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example | LANXESS DEUTSCHLAND GMBH (DE) | 2007-12-27 | — | — | US | disclosed |
| US-7230136-B2 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2007-06-12 | — | — | US | disclosed |
| EP-1312598-B1 | Process for producing aldehyde | MITSUBISHI CHEM CORP (JP) | 2005-02-16 | — | — | EP | disclosed |
| EP-1008581-B1 | Process for producing aldehyde | MITSUBISHI CHEM CORP (JP) | 2004-04-21 | — | — | EP | disclosed |
| US-20030229240-A1 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | US | disclosed |
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-6610891-B1 | Reduces degradation or decomposition of catalyst | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-08-26 | — | — | US | disclosed |
| US-6583324-B2 | By hydroformylation with rhodium complex catalyst containing an organic phosphite ligand; preventing catalyst poisoning by having the aldehyde remain in the catalyst solution in the separation step | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-06-24 | — | — | US | disclosed |
| EP-1312598-A1 | Process for producing aldehyde | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-20020049355-A1 | Process for producing aldehyde | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-04-25 | — | — | US | disclosed |
| US-6291717-B1 | REACTING OLEFINIC COMPOUND WITH CARBON MONOXIDE AND HYDROGEN IN THE PRESENCE OF A RHODIUM COMPLEX CATALYST COMPRISING RHODIUM AND ORGANIC PHOSPHITE IN REACTION ZONE; SEPARATING CATALYST AND ALDEHYDE; RECYCLING CATALYST SOLUTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-09-18 | — | — | US | disclosed |
| US-6265620-B1 | REACTING OLEFINIC COMPOUND WITH CARBON MONOXIDE AND HYDROGEN IN PRESENCE OF CATALYST CONTAINING METAL OF GROUP 8 TO 10 AND TRIVALENT ORANIC PHOSPHORUS COMPOUND TO PRODUCE ALDEHYDE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1008581-A1 | Process for producing aldehyde | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049355-A1 | Process for producing aldehyde | ALDH2, OGDH, HAO2 | ALDH1A1 16/4885HSD17B10 239/4885CYP1B1 1531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.