SCHEMBL28830779

SCHEMBL28830779

CCC(CC)c1ccc2c(c1)CCCC2

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ALDH1A1 P00352 4/20 0.40
KMT2A Q03164 2/20 0.40
HTT P42858 2/20 0.40
HSP90AA1 P07900 1/20 0.40
GAA P10253 1/20 0.40
MEN1 O00255 1/20 0.40
KEAP1 Q14145 7/20 0.39
NFE2L2 Q16236 7/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP3A4 P08684 1/20 0.38
LMNA P02545 1/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
TSHR P16473 1/20 0.36
ADRA2A P08913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18707502 0.83 HDAC8 (0.39) NPC1RAB9AALDH1A1KMT2AHTT
SCHEMBL24023602 0.82 ALDH1A1 (0.44) ALDH1A1KMT2AHTTHSP90AA1GAA
SCHEMBL20238711 0.81 SLC6A4 (0.43) NPC1RAB9AALDH1A1KMT2AHTT
SCHEMBL25596388 0.79 ADRA2A (0.37) NPC1RAB9AALDH1A1KMT2AHTT
SCHEMBL18500386 0.79 MAOA (0.45) KMT2AMEN1
SCHEMBL23134243 0.78 ALDH1A1 (0.40) NPC1RAB9AALDH1A1KMT2AHTT
SCHEMBL18500444 0.78 L3MBTL3 (0.39) CYP2D6
SCHEMBL9859659 0.77 KMT2A (0.46) ALDH1A1KMT2AHTTHSP90AA1GAA
SCHEMBL12844790 0.77 ADRA2A (0.34) ADRA2A
SCHEMBL20785017 0.77 ASIC3 (0.50) ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114019044-B Method for analyzing structural characteristics of carbon skeleton of water-soluble organic molecules 中国石油大学(北京) 2023-07-04 CN disclosed
CN-114019044-A Method for analyzing structural characteristics of water-soluble organic molecular carbon skeleton 中国石油大学(北京) 2022-02-08 CN disclosed