Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21377667 | 0.85 | ADAMTS5 (0.55) | KMT2ATDP1MEN1ALDH1A1KDM4E | |
| SCHEMBL6216328 | 0.80 | NPC1 (0.52) | MAOBMAOAXDHNPC1RAB9A | |
| SCHEMBL31403188 | 0.80 | MAOB (0.63) | MAOBMAOAXDHNPC1RAB9A | |
| SCHEMBL4709886 | 0.80 | APP (0.56) | MAOBMAOACSF1RXDHNPC1 | |
| SCHEMBL31496915 | 0.80 | FFAR1 (0.52) | MAOBMAOAXDHNPC1RAB9A | |
| SCHEMBL9861768 | 0.79 | SMN1; SMN2 (0.58) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL16950440 | 0.79 | ALDH1A1 (0.56) | MAOBMAOAKMT2AMEN1ALDH1A1 | |
| SCHEMBL23143207 | 0.78 | XDH (0.51) | ALDH1A1KDM4EXDHNPC1RAB9A | |
| SCHEMBL16959750 | 0.78 | XDH (0.41) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL5973009 | 0.77 | ENPP2 (0.53) | MAOBMAOAXDHNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026081-B | Pyridone derivatives as selective cytotoxic agents against HIV-infected cells | 默沙东有限责任公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-114026081-A | Pyridone derivatives as selective cytotoxic agents against HIV-infected cells | 默沙东公司 | 2022-02-08 | — | — | CN | disclosed |