Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12517075 | 0.94 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL11005043 | 0.94 | HPGD (0.60) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL21377667 | 0.94 | ADAMTS5 (0.55) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL30341701 | 0.92 | APP (0.60) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL348043 | 0.92 | APP (0.60) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6545571 | 0.87 | MAPT (0.73) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL13725919 | 0.86 | AMY1A (0.60) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL6215450 | 0.83 | TRPA1 (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL21473709 | 0.82 | POLB (0.62) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL9722182 | 0.82 | POLB (0.62) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165769-B1 | POLYFUNCTIONAL STYRYLOXY COMPOUNDS AND METHOD OF FORMING A CROSS-LINKED POLYMER | LOCTITE (IRELAND) Ltd. (IE) | 1991-08-21 | — | — | EP | disclosed |
| US-4732956-A | Styryloxy resins and compositions thereof | LOCTITE (IRELAND) LTD. (IE) | 1988-03-22 | — | — | US | disclosed |
| EP-0220831-A2 | Styryloxy resins and polymerization process | LOCTITE (IRELAND) Ltd. (IE) | 1987-05-06 | — | — | EP | disclosed |
| EP-0165769-A2 | Polyfunctional styryloxy compounds and method of forming a cross-linked polymer | LOCTITE (IRELAND) Ltd. (IE) | 1985-12-27 | — | — | EP | disclosed |