Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27881398 | 0.82 | TSHR (0.48) | ALDH1A1NPSR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10801519 | 0.78 | KMT2A (0.46) | ALDH1A1LMNAMAPTHTTPOLB | |
| SCHEMBL22116022 | 0.77 | LMNA (0.70) | NPBWR1MCHR1ALDH1A1LMNAMAPT | |
| SCHEMBL22137282 | 0.77 | LMNA (0.70) | NPBWR1MCHR1ALDH1A1LMNAMAPT | |
| SCHEMBL10804963 | 0.76 | MEN1 (0.48) | ALDH1A1LMNAMAPTNPSR1MITF | |
| SCHEMBL4894349 | 0.75 | LMNA (0.68) | NPBWR1MCHR1ALDH1A1LMNAMAPT | |
| SCHEMBL4900948 | 0.74 | VCAM1 (0.71) | NPBWR1MCHR1ALDH1A1LMNAMAPT | |
| SCHEMBL28448328 | 0.72 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTNPSR1HTT | |
| SCHEMBL2041750 | 0.72 | KMT2A (0.80) | NPBWR1MCHR1ALDH1A1LMNAMAPT | |
| SCHEMBL10803968 | 0.71 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916500-A | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 欧洲筛选有限公司 | 2016-08-31 | — | — | CN | disclosed |