Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049321 | 0.89 | ALDH1A1 (0.40) | TDP1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL28026010 | 0.86 | ALDH1A1 (0.38) | TDP1ALDH1A1PKMATMLMNA | |
| SCHEMBL28299375 | 0.85 | KCNA3 (0.43) | ALDH1A1NPC1RAB9APKMATM | |
| SCHEMBL28030487 | 0.83 | CHRM2 (0.41) | TDP1ATM | |
| SCHEMBL28073265 | 0.82 | ALDH1A1 (0.37) | TDP1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28049253 | 0.81 | LMNA (0.47) | ALDH1A1KMT2AMEN1CYP2C19KDM4E | |
| SCHEMBL28086157 | 0.81 | LMNA (0.51) | ALDH1A1KMT2AMEN1CYP2C19KDM4E | |
| SCHEMBL27999947 | 0.80 | GAA (0.53) | ALDH1A1KMT2AMEN1CYP2C19KDM4E | |
| Hydrochloric Acid SCHEMBL28314858 | 0.80 | LMNA (0.54) | ALDH1A1KMT2AMEN1SMN1; SMN2CYP2C19 | |
| SCHEMBL28823469 | 0.79 | CYP3A4 (0.36) | TDP1ALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103403002-B | Thiazolylphenyl-benzderivativesido derivativesido as inhibitors of kinases | 内尔维阿诺医学科学有限公司 | 2016-06-22 | — | — | CN | disclosed |