Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299375 | 0.86 | KCNA3 (0.43) | ALDH1A1ATMLMNACNR1CNR2 | |
| SCHEMBL28049321 | 0.84 | ALDH1A1 (0.40) | ALDH1A1ATMLMNACNR1CNR2 | |
| SCHEMBL28026010 | 0.84 | ALDH1A1 (0.38) | ALDH1A1ATMLMNACNR1CNR2 | |
| SCHEMBL28832222 | 0.82 | TDP1 (0.51) | ALDH1A1ATMLMNAPKMTSHR | |
| SCHEMBL28049253 | 0.82 | LMNA (0.47) | ALDH1A1ATMLMNACYP2D6CYP1A2 | |
| SCHEMBL28086157 | 0.82 | LMNA (0.51) | ALDH1A1ATMLMNACYP2D6CYP1A2 | |
| SCHEMBL27851589 | 0.81 | L3MBTL3 (0.36) | ALDH1A1LMNACNR1CNR2CYP2D6 | |
| SCHEMBL28030487 | 0.81 | CHRM2 (0.41) | ATMCHRM3HRH1CCR3KCNH2 | |
| SCHEMBL27999947 | 0.81 | GAA (0.53) | ALDH1A1LMNACYP2D6CHRM3CYP1A2 | |
| Hydrochloric Acid SCHEMBL28314858 | 0.81 | LMNA (0.54) | ALDH1A1ATMLMNACYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109966294-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维爱尔兰无限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109897038-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维爱尔兰无限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-106397418-A | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBVIE公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-103167867-B | Solid dispersion containing apoptosis-inducing medicament | ABBVIE 公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-103153993-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC. (BS) | 2016-06-01 | — | — | CN | disclosed |
| CN-105308038-A | Enhancer of zeste homolog 2 inhibitors | GLAXOSMITHKLINE IP NO 2 LTD | 2016-02-03 | — | — | CN | disclosed |
| CN-104906100-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBOTT LAB | 2015-09-16 | — | — | CN | disclosed |
| CN-104876927-A | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LAB | 2015-09-02 | — | — | CN | disclosed |
| CN-102448959-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE BAHAMAS LTD | 2015-06-17 | — | — | CN | disclosed |