Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | SI | P14410 | 4/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370820 | 0.84 | MEN1 (0.59) | GPR84FFAR1MGAMGAASI | |
| SCHEMBL10821238 | 0.83 | HTR2A (0.49) | GPR84FFAR1MGAMGAASI | |
| SCHEMBL11385196 | 0.80 | GPR84 (0.58) | GPR84FFAR1MGAMGAASI | |
| SCHEMBL1849664 | 0.78 | NOD2 (0.53) | GPR84FFAR1MGAMGAASI | |
| SCHEMBL20913022 | 0.78 | MEN1 (0.54) | GPR84FFAR1MGAMGAASI | |
| SCHEMBL11868301 | 0.78 | MEN1 (0.50) | GPR84FFAR1MGAMGAASI | |
| SCHEMBL9250842 | 0.77 | KMT2A (0.56) | GPR84FFAR1MGAMGAASI | |
| SCHEMBL7047429 | 0.76 | MEN1 (0.59) | GPR84FFAR1MGAMGAASI | |
| SCHEMBL1893849 | 0.76 | MEN1 (0.59) | GPR84FFAR1MGAMGAASI | |
| SCHEMBL1852207 | 0.76 | ALDH1A1 (0.53) | GPR84FFAR1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292557-B | Pyridopyrimidinone mesoion derivative containing indole unit and preparation method and application thereof | 贵州大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-113292557-A | Pyridopyrimidinone mesoion derivative containing indole unit and preparation method and application thereof | 贵州大学 | 2021-08-24 | — | — | CN | disclosed |