SCHEMBL28837871

SCHEMBL28837871

Cc1ccc(OC=O)cc1.[MgH2]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.46
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
CYP2A6 P11509 1/20 0.44
LMNA P02545 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
RELA Q04206 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
TEAD4 Q15561 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
DRD2 P14416 1/20 0.38
DRD4 P21917 1/20 0.38
DRD3 P35462 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95902 0.97 ACHE (0.48) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL18805146 0.91 TEAD4 (0.52) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL4570686 0.91 ACHE (0.42) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL25479947 0.85 DRD2 (0.53) MEN1KMT2APOLBDRD2DRD4
SCHEMBL4570682 0.85 MAPT (0.46) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL15500191 0.85 TSHR (0.38) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL6454577 0.84 ALDH1A1 (0.38) CYP2A6LMNACA1CA2CA9
SCHEMBL12325325 0.83 TSHR (0.41) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL12557368 0.82 NPC1 (0.63) CYP3A4TSHRCYP2A6MEN1KMT2A
SCHEMBL20274359 0.80 ALOX5 (0.35) ACHECYP3A4TSHRCYP2A6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106348376-A Method of separating pollutants from waste water and system thereof 诚信工业有限公司 2017-01-25 CN disclosed