SCHEMBL28838079

SCHEMBL28838079

C1=CC(C(c2ccccc2)(c2ccccc2)C2c3ccccc3-c3ccccc32)C=C1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.32
GPR3 P46089 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1539669 0.84 GPR3 (0.38) KCNN4GPR3HTR2A
SCHEMBL26988518 0.80 PTPN1 (0.35)
SCHEMBL26988456 0.79 ALDH1A1 (0.38)
SCHEMBL38651760 0.79 ALDH1A1 (0.38)
SCHEMBL26988423 0.78 CNR1 (0.40)
SCHEMBL38651668 0.73 GPR3 (0.38) GPR3HTR2A
SCHEMBL23510853 0.72 RARA (0.35)
SCHEMBL12815225 0.71 GPR3 (0.38) KCNN4GPR3HTR2A
SCHEMBL12815279 0.68 GPR3 (0.40) KCNN4GPR3HTR2A
SCHEMBL8970933 0.68 TSHR (0.42) KCNN4GPR3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101726-A1 HYDROCARBYL SILYL-SUBSTITUTED ANSA-METALLOCENES AND PROCESS FOR PREPARING LOW MELT ELASTICITY POLYOLEFINS FORMOSA PLASTICS CORPORATON, U.S.A. (US) 2026-05-15 WO disclosed
US-20260131320-A1 HYDROCARBYL SILYL-SUBSTITUTED ANSA-METALLOCENES AND PROCESS FOR PREPARING LOW MELT ELASTICITY POLYOLEFINS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2026-05-14 US disclosed
CN-115010838-A Olefin polymerization method and polyolefin obtained by same 中国石油化工股份有限公司 2022-09-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260131320-A1 HYDROCARBYL SILYL-SUBSTITUTED ANSA-METALLOCENES AND PROCESS FOR PREPARING LOW MELT ELASTICITY POLYOLEFINS SMC1A, HSPA4L, SMC4 KCNN4 2796/4885GPR3 4031/4885HTR2A 2547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.