SCHEMBL28838437

SCHEMBL28838437

COS(=O)(=O)O.Nc1nc(C(=O)O)n[nH]1

nearest known ligand 0.33

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 2/20 0.32
GAA P10253 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL351234 0.84
Sulfuric Acid SCHEMBL28838438 0.78 TSHR (0.38) ALDH1A1KDM4E
Sulfuric Acid SCHEMBL29044137 0.77 TSHR (0.37) ALDH1A1KDM4E
SCHEMBL28518756 0.73 CGAS (0.36) ALDH1A1KDM4EGAA
SCHEMBL11199351 0.69 LMNA (0.35) ALDH1A1KDM4EGAA
SCHEMBL2534433 0.66 PDE4D (0.47) ALDH1A1KDM4EGAA
Hydrochloric Acid SCHEMBL17747830 0.65 MAP4K1 (0.34) ALDH1A1
SCHEMBL6771598 0.64
Guanazole SCHEMBL6030091 0.64 ALDH1A1 (0.36) ALDH1A1KDM4EGAA
Bicarbonate SCHEMBL9356234 0.63 CA2 (0.41) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514729-B Preparation process of 1,2, 4-triazole-3-carboxylic acid methyl ester 济南明鑫制药股份有限公司 2024-04-16 CN disclosed
CN-116514729-A Preparation process of 1,2, 4-triazole-3-carboxylic acid methyl ester 济南明鑫制药股份有限公司 2023-08-01 CN disclosed
CN-106432111-A Method for synthesizing ribavirin drug intermediate 1,2,4-triazole-3-carboxylic acid methyl ester 厦门莱恩斯特信息科技有限公司 2017-02-22 CN disclosed