Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28338776 | 0.86 | P2RX7 (0.44) | JAK2JAK3PTGS2BRAFTUBB4A | |
| Ethoxycarbonyl Group SCHEMBL28168775 | 0.84 | MAPK14 (0.52) | PTGS2MAPK14RET | |
| Ethoxycarbonyl Group SCHEMBL28678157 | 0.79 | TUBB4A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Ethoxycarbonyl Group SCHEMBL28339303 | 0.77 | GAK (0.39) | JAK2PTGS2TUBB4ATUBBTUBA3C | |
| Ethoxycarbonyl Group SCHEMBL27908786 | 0.77 | TUBB1 (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Ethoxycarbonyl Group SCHEMBL28341231 | 0.76 | GAK (0.39) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28880746 | 0.76 | PTGS2 (0.45) | PTGS2TUBB4ATUBBTUBA3CTUBA1B | |
| Ethoxycarbonyl Group SCHEMBL28844709 | 0.73 | P2RX7 (0.47) | MAPK14IDO1TDO2 | |
| SCHEMBL1171995 | 0.73 | EPHB4 (0.59) | JAK2JAK3BRAFRETEGFR | |
| SCHEMBL2982161 | 0.72 | RET (0.54) | JAK2JAK3BRAFTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-A | Benzazole compounds and preparation method thereof, pharmaceutical composition and purposes | INST MATERIA MEDICA CAMS | 2019-11-22 | — | — | CN | disclosed |