Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM5C | P41229 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845651 | 0.89 | GPR52 (0.54) | GPR52DNMT1DNMT3AGAKALDH1A1 | |
| SCHEMBL28845687 | 0.88 | ALDH1A1 (0.57) | GPR52DNMT1DNMT3AAURKAGAK | |
| SCHEMBL28845643 | 0.87 | GPR52 (0.59) | GPR52DNMT1DNMT3AGAKALDH1A1 | |
| SCHEMBL28845637 | 0.86 | DNMT1 (0.52) | GPR52DNMT1DNMT3AAURKAGAK | |
| SCHEMBL28845675 | 0.86 | DNMT1 (0.68) | DNMT1DNMT3AAURKALMNAGAK | |
| SCHEMBL29140025 | 0.83 | GAK (0.54) | GPR52DNMT1DNMT3ALMNAGAK | |
| SCHEMBL28845682 | 0.82 | DNMT1 (0.54) | CCNCCDK8DNMT1DNMT3AMLYCD | |
| SCHEMBL29200469 | 0.80 | GAK (0.55) | DNMT1DNMT3AAURKAGAKPRKD3 | |
| SCHEMBL28845648 | 0.80 | NPSR1 (0.56) | GPR52DNMT1DNMT3AAURKAGAK | |
| SCHEMBL28845680 | 0.79 | GAK (0.51) | GPR52DNMT1DNMT3AAURKAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | disclosed |