Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 3/20 | 0.50 |
| ▸ | GSK3A | P49840 | 5/20 | 0.47 |
| ▸ | GSK3B | P49841 | 5/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.47 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.47 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.47 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.47 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.47 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.47 |
| ▸ | STK3 | Q13188 | 1/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.47 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200469 | 0.86 | GAK (0.55) | GAKGSK3AGSK3BCLK4KDR | |
| SCHEMBL28845637 | 0.85 | DNMT1 (0.52) | GAKGSK3AGSK3BCLK4KDR | |
| SCHEMBL28845687 | 0.83 | ALDH1A1 (0.57) | GAKGSK3AGSK3BCLK4KDR | |
| SCHEMBL28845648 | 0.81 | NPSR1 (0.56) | GAKGSK3AGSK3BCLK4KDR | |
| SCHEMBL28845667 | 0.81 | KCNK3 (0.55) | GAKGSK3AGSK3BCLK4KDR | |
| SCHEMBL28845675 | 0.81 | DNMT1 (0.68) | GAKGSK3AGSK3BCLK4KDR | |
| SCHEMBL28845651 | 0.80 | GPR52 (0.54) | GAKGSK3AGSK3BCLK4KDR | |
| SCHEMBL29809955 | 0.80 | MEN1 (0.61) | GAKGSK3AGSK3BCLK4KDR | |
| SCHEMBL28845693 | 0.80 | MEN1 (0.61) | GAKGSK3AGSK3BCLK4KDR | |
| SCHEMBL29200480 | 0.79 | GAK (0.57) | GAKGSK3AGSK3BCLK4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | disclosed |