Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583224 | 0.81 | BCAT2 (0.50) | BCAT2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL6205026 | 0.79 | TDP1 (0.44) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29950282 | 0.72 | LMNA (0.54) | BCAT2ALDH1A1MAPTTSHRTDP1 | |
| SCHEMBL4332774 | 0.72 | ALDH1A1 (0.40) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30986109 | 0.72 | ALDH1A1 (0.62) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2636763 | 0.72 | ALDH1A1 (0.62) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL995083 | 0.72 | LMNA (0.54) | BCAT2ALDH1A1MAPTTSHRTDP1 | |
| SCHEMBL27505005 | 0.72 | TDP1 (0.44) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17157028 | 0.72 | ALDH1A1 (0.52) | BCAT2POLBALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1788703 | 0.71 | BCAT2 (0.59) | BCAT2ALDH1A1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734674-B | Aniline WDR5 protein-protein interaction inhibitor and preparation method and application thereof | 中国药科大学 | 2022-08-26 | — | — | CN | disclosed |