Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28156842 | 0.80 | NOD2 (0.51) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL28156800 | 0.78 | KMT2A (0.46) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL28846115 | 0.78 | MTNR1A (0.56) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL28156129 | 0.75 | KMT2A (0.46) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL3301323 | 0.73 | NOD2 (0.64) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL3259707 | 0.67 | NOD2 (0.71) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL15396041 | 0.67 | CYP3A4 (0.73) | KMT2AMEN1CYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL28669136 | 0.66 | NOD2 (0.70) | NOD2NOD1KMT2AMEN1KDM4E | |
| SCHEMBL11688236 | 0.66 | L3MBTL1 (0.56) | NOD2NOD1KMT2AMEN1CYP3A4 | |
| SCHEMBL8754518 | 0.66 | CYP3A4 (0.65) | KMT2AMEN1CYP3A4KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831533-A | A kind of synthetic method of tryptophol and tryptamines analog derivative | 北京大学 | 2017-06-13 | — | — | CN | disclosed |