⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337580 | 0.79 | — | — | |
| SCHEMBL8561684 | 0.79 | — | — | |
| SCHEMBL288480 | 0.77 | ALDH1A1 (0.53) | — | |
| SCHEMBL18446 | 0.77 | ALDH1A1 (0.53) | — | |
| SCHEMBL5322592 | 0.75 | — | — | |
| SCHEMBL733363 | 0.74 | — | — | |
| SCHEMBL3029208 | 0.74 | — | — | |
| SCHEMBL9748858 | 0.74 | — | — | |
| SCHEMBL4630435 | 0.74 | NAAA (0.52) | — | |
| SCHEMBL2948744 | 0.72 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108113895-A | Cosmetic foam containing UV filter from emulsion containing sodium cetearyl sulfate and glyceryl monostearate | 拜尔斯道夫股份有限公司 | 2018-06-05 | — | — | CN | claimed |
| CN-106983671-A | Sunscreen agents containing titanium dioxide | 拜尔斯道夫股份有限公司 | 2017-07-28 | — | — | CN | claimed |
| CN-106456495-A | Sunscreen formulations with reduced tendency to stain fabrics III | 拜尔斯道夫股份有限公司 | 2017-02-22 | — | — | CN | claimed |
| US-9073956-B1 | Dihydro-1H-phosphole 1-oxide derivatives and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2015-07-07 | — | — | US | claimed |
| EP-2517709-A1 | MEDICAL AND PHARMACEUTICAL USE OF 2', 2-BIS-THIAZOLE NON-NUCLEOSIDE COMPOUNDS AS HEPATITIS C VIRUS INHIBITOR | Shanghai Institute of Materia Medica (CN) | 2012-10-31 | — | — | EP | claimed |
| US-20120264793-A1 | Pharmaceutical Use of 2',2-Bis-Thiazole Non-Nucleoside Compounds as Hepatitis C Virus Inhibitor | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2012-10-18 | — | — | US | claimed |
| EP-1454903-B9 | Thiadiazoline derivatives for treating cancer | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-10-05 | — | — | EP | claimed |
| EP-1454903-B1 | Thiadiazoline derivatives for treating cancer | KYOWA HAKKO KIRIN CO LTD (JP) | 2010-09-08 | — | — | EP | claimed |
| US-20100056569-A1 | Heterocyclic Non-Nucleoside Compounds, Their Preparation, Pharmaceutical Composition And Their Use As Antiviral Agents | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2010-03-04 | — | — | US | claimed |
| EP-2030974-A1 | HETEROCYCLIC NON-NUCLEOSIDE COMPOUNDS, THEIR PEPARATION, PHARMACEUTICAL COMPOSITION AND THEIR USE AS ANTIVIRAL AGENTS | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2009-03-04 | — | — | EP | claimed |
| EP-0785938-A1 | FUSED PYRROLOCARBAZOLES | CEPHALON, INC. (US) | 1997-07-30 | — | — | EP | claimed |
| JP-2633087-B2 | — | — | 1997-07-23 | — | — | JP | claimed |
| US-5594009-A | KINASE INHIBITORS, TROPHIC FACTOR-INDUCED ACTIVITY ENHANCEMENT, CELL SURVIVAL | CEPHALON, INC. (US) | 1997-01-14 | — | — | US | claimed |
| US-5591855-A | KINASE INHIBITORS, TROPHIC FACTOR-INDUCED ACTIVITY ENHANCEMENT, CELL SURVIVAL | CEPHALON, INC. (US) | 1997-01-07 | — | — | US | claimed |
| WO-1996011933-A1 | FUSED PYRROLOCARBAZOLES | CEPHALON, INC. (US) | 1996-04-25 | — | — | WO | claimed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | claimed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | claimed |
| EP-0204534-A2 | Quinazolinone compounds and processes for the preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1986-12-10 | — | — | EP | claimed |
| US-4174445-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-13 | — | — | US | claimed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | claimed |