SCHEMBL28848753

SCHEMBL28848753

CCOCc1cncnc1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.32
P2RX7 Q99572 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28672290 0.85 TSHR (0.39)
SCHEMBL21507385 0.77 ALDH1A1 (0.32)
SCHEMBL1145817 0.75
SCHEMBL19049417 0.74 HSD11B1 (0.34)
SCHEMBL774717 0.74 CHRNB2 (0.52) NAMPT
SCHEMBL13645569 0.74 CYP11B1 (0.39)
SCHEMBL3865554 0.73 LPL (0.33) NAMPT
SCHEMBL14968355 0.73 P2RX7 (0.37) P2RX7
SCHEMBL7547843 0.73 CHRNB2 (0.39)
SCHEMBL19002693 0.73 HSD11B1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106998692-A MK2 inhibitor and its purposes 西建卡尔有限责任公司 2017-08-01 CN disclosed