Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849438 | 0.81 | MAPT (0.42) | CHRM2CHRM1MAPTKMT2AMEN1 | |
| SCHEMBL28849437 | 0.77 | MAPT (0.39) | CHRM2CHRM1MAPTKMT2AMEN1 | |
| SCHEMBL28849453 | 0.77 | TSHR (0.41) | CHRM1MAPTKMT2AMEN1TRPA1 | |
| SCHEMBL28849430 | 0.77 | MAPT (0.39) | CHRM2CHRM1MAPTKMT2AMEN1 | |
| SCHEMBL28849440 | 0.77 | TRPA1 (0.48) | MAPTKMT2AALDH1A1MEN1TRPA1 | |
| SCHEMBL28849431 | 0.77 | TRPA1 (0.41) | MAPTKMT2AMEN1TRPA1HPGD | |
| SCHEMBL28849416 | 0.76 | MAPT (0.43) | MAPTKMT2AALDH1A1MEN1TRPA1 | |
| SCHEMBL28849415 | 0.75 | SLC6A4 (0.42) | CHRM2CHRM1KMT2AMEN1SLC6A2 | |
| SCHEMBL9773125 | 0.75 | DRD2 (0.52) | ALDH1A1 | |
| SCHEMBL28849414 | 0.74 | SLC6A2 (0.44) | CHRM2CHRM1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108875-A | Nitrogen-containing heteroarene chiral cyclic alcohol constructed by visible light asymmetric catalysis, and preparation method and application thereof | 河南师范大学 | 2022-09-27 | — | — | CN | disclosed |