Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950696 | 1.00 | KMT2A (0.48) | KMT2ALMNADDB1CRBNGRM2 | |
| SCHEMBL29950579 | 0.72 | USP2 (0.48) | KMT2ALMNADRD2DRD3DRD4 | |
| SCHEMBL28849452 | 0.72 | USP2 (0.48) | KMT2ALMNADRD2DRD3DRD4 | |
| SCHEMBL29950746 | 0.72 | UBE2T (0.43) | KMT2ADRD2DRD3DRD4NPC1 | |
| SCHEMBL28849441 | 0.72 | UBE2T (0.43) | KMT2ADRD2DRD3DRD4NPC1 | |
| SCHEMBL2867643 | 0.72 | LMNA (0.49) | KMT2ALMNAGRM2DRD2DRD3 | |
| SCHEMBL14685201 | 0.72 | DDB1 (0.58) | KMT2ALMNADDB1CRBNGRM2 | |
| SCHEMBL4989694 | 0.72 | SLC6A2 (0.51) | KMT2ASMN1; SMN2MEN1SLC6A2SLC6A4 | |
| SCHEMBL28849419 | 0.70 | TRPA1 (0.58) | KMT2ALMNAMEN1SLC6A2SLC6A4 | |
| SCHEMBL898940 | 0.70 | SLC6A2 (0.49) | KMT2ASMN1; SMN2MEN1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108875-A | Nitrogen-containing heteroarene chiral cyclic alcohol constructed by visible light asymmetric catalysis, and preparation method and application thereof | 河南师范大学 | 2022-09-27 | — | — | CN | disclosed |