Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL27769566 | 0.92 | ALDH1A1 (0.54) | ALDH1A1RAB9ATSHRGAATDP1 | |
| SCHEMBL29674812 | 0.88 | FFAR1 (0.53) | ALDH1A1 | |
| SCHEMBL132773 | 0.84 | ALDH1A1 (0.78) | ALDH1A1TDP1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL11844391 | 0.83 | GAA (0.51) | RAB9ATSHRGAATDP1NPC1 | |
| SCHEMBL8886664 | 0.83 | TSHR (0.48) | ALDH1A1RAB9ATSHRGAATDP1 | |
| SCHEMBL11740343 | 0.83 | TSHR (0.48) | ALDH1A1RAB9ATSHRGAATDP1 | |
| SCHEMBL17316360 | 0.82 | KDM1A (0.50) | ALDH1A1RAB9ATSHRCYP2A6MAPT | |
| SCHEMBL43788 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1CYP3A4MAOB | |
| SCHEMBL3292009 | 0.81 | ALDH1A1 (0.58) | ALDH1A1RAB9ATSHRGAATDP1 | |
| Hydrochloric Acid SCHEMBL11844386 | 0.81 | GAA (0.50) | RAB9ATSHRGAATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200291222-A1 | ORGANOPHOSPHORUS FLAME-RETARDANT TETRAZINES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2020-09-17 | — | — | US | claimed |
| EP-1004574-B1 | Process for producing cyanobenzyl compounds | SHOWA DENKO KK (JP) | 2003-03-19 | — | — | EP | claimed |
| US-6187945-B1 | TRANSFORMING AN AMINOMETHYL GROUP OF A CYANOBENZYLAMINE COMPOUND INTO A HYDROXYMETHYL GROUP, A HALOMETHYL GROUP, OR AN ACYLOXYMETHYL GROUP BY DIAZOTIZATION AND HYDROXYLATION, HALOGENATION OR ACYLATION | SHOWA DENKO K.K. (JP) | 2001-02-13 | — | — | US | claimed |
| EP-1004574-A1 | Process for producing cyanobenzyl compounds | Showa Denko Kabushiki Kaisha (JP) | 2000-05-31 | — | — | EP | claimed |
| CN-112851538-B | Method for promoting acylation of amine or alcohol by carbon dioxide | 中国科学院兰州化学物理研究所 | 2022-05-20 | — | — | CN | disclosed |
| CN-112851538-A | Method for promoting acylation of amine or alcohol by carbon dioxide | 中国科学院兰州化学物理研究所 | 2021-05-28 | — | — | CN | disclosed |
| US-10954376-B2 | Organophosphorus flame-retardant tetrazines | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2021-03-23 | — | — | US | disclosed |
| US-20200291222-A1 | ORGANOPHOSPHORUS FLAME-RETARDANT TETRAZINES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2020-09-17 | — | — | US | disclosed |
| US-10577327-B2 | Pyridine based ionic fluoride for catalyzing indole and tetrazole formation | KING ABDULAZIZ UNIVERSITY (SA) | 2020-03-03 | — | — | US | disclosed |
| CN-103764635-B | New trifluoromethyl-oxadiazole derivative and the purposes in disease treatment thereof | NOVARTIS AG (CH) | 2016-01-20 | — | — | CN | disclosed |
| US-7825149-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2010-11-02 | — | — | US | disclosed |
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
| US-20040092582-A1 | Furoisoquinoline derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1004574-B1 | Process for producing cyanobenzyl compounds | SHOWA DENKO KK (JP) | 2003-03-19 | — | — | EP | disclosed |
| EP-1270577-A1 | FUROISOQUINOLINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6485657-B1 | Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer | TEIJIN, LIMITED (JP) | 2002-11-26 | — | — | US | disclosed |
| US-6187945-B1 | TRANSFORMING AN AMINOMETHYL GROUP OF A CYANOBENZYLAMINE COMPOUND INTO A HYDROXYMETHYL GROUP, A HALOMETHYL GROUP, OR AN ACYLOXYMETHYL GROUP BY DIAZOTIZATION AND HYDROXYLATION, HALOGENATION OR ACYLATION | SHOWA DENKO K.K. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |
| EP-1004574-A1 | Process for producing cyanobenzyl compounds | Showa Denko Kabushiki Kaisha (JP) | 2000-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577327-B2 | Pyridine based ionic fluoride for catalyzing indole and tetrazole formation | FLI1, ABL1, INMT | ALDH1A1 1278/4885RAB9A 1497/4885TSHR 266/4885 |
| US-20040092582-A1 | Furoisoquinoline derivatives, process for producing the same and use thereof | PDE3B, PDE5A, PDE3A | ALDH1A1 572/4885RAB9A 742/4885TSHR 2457/4885 |
| US-20100056497-A1 | AMIDE DERIVATIVE | REN, AGTR1, AGTR2 | ALDH1A1 348/4885RAB9A 258/4885TSHR 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.