Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | AGXT | P21549 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27474336 | 0.81 | RAB9A (0.50) | PTK2MTNR1AMTNR1BIDO1LTA4H | |
| SCHEMBL2099512 | 0.76 | CHRM2 (0.66) | CHRM2CHRM1CHRM3HTR1BTAAR1 | |
| SCHEMBL20773126 | 0.76 | HTR1B (0.49) | PTK2CHRM2CHRM1CHRM3HTR1B | |
| SCHEMBL12863944 | 0.76 | PTK2 (0.57) | PTK2MTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL11555567 | 0.75 | DHFR (0.46) | PTK2CHRM2CHRM1CHRM3HTR1B | |
| SCHEMBL27912754 | 0.72 | ALDH1A1 (0.46) | MTNR1AMTNR1BDHFRCMA1 | |
| SCHEMBL2092574 | 0.71 | LTA4H (0.67) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL31739258 | 0.71 | LTA4H (0.67) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL21157861 | 0.71 | GPR55 (0.48) | PTK2CHRM2CHRM1CHRM3HTR1B | |
| SCHEMBL1186047 | 0.70 | NOTUM (1.00) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104936963-B | Sulfide derivative as kinases inhibitor | 普罗齐纳斯有限公司 | 2017-11-28 | — | — | CN | disclosed |