Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28855326

C1CCOC1.CC1(C)CCC(Cc2ccc(Cl)cc2)C1=O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.40
MAOB P27338 3/20 0.38
TRPA1 O75762 1/20 0.36
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.34
PDE1A P54750 2/20 0.33
PDE1B Q01064 2/20 0.33
PDE1C Q14123 2/20 0.33
CCR5 P51681 1/20 0.32
CCR2 P41597 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5350084 0.90 MAOB (0.40) MAOBTRPA1ALDH1A1TSHRCCR5
SCHEMBL9147038 0.85 TRPA1 (0.40) HSD11B1MAOBTRPA1ALDH1A1TSHR
SCHEMBL9148468 0.83 HSD11B1 (0.40) HSD11B1MAOBTRPA1ALDH1A1TSHR
SCHEMBL15822934 0.83 FFAR1 (0.44) MAOBTRPA1ALDH1A1TSHR
Formic Acid Methyl Ester SCHEMBL27487647 0.82 MAOB (0.35) MAOBTRPA1ALDH1A1TSHRCCR5
SCHEMBL17135362 0.81 TSHR (0.39) MAOBTRPA1ALDH1A1TSHRCCR5
Ethoxycarbonyl Group SCHEMBL27506197 0.79 KMT2A (0.36) MAOBTRPA1ALDH1A1TSHRCCR5
SCHEMBL9144305 0.77 L3MBTL1 (0.40) TRPA1ALDH1A1CCR5
SCHEMBL31440790 0.76 HTR6 (0.42) ALDH1A1TSHR
SCHEMBL1785146 0.75 MAOB (0.42) HSD11B1MAOBALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104710372-B Metconazole and preparation method thereof 上海交通大学 2017-12-15 CN claimed