Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856183 | 0.80 | SIGMAR1 (0.34) | SIGMAR1MEN1KMT2A | |
| SCHEMBL5521576 | 0.77 | MEN1 (0.41) | SIGMAR1MEN1KMT2A | |
| SCHEMBL28199273 | 0.77 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL27618554 | 0.74 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL23869788 | 0.71 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2SIGMAR1ALDH1A1 | |
| SCHEMBL6622116 | 0.70 | KMT2A (0.48) | SIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL2011410 | 0.69 | SIGMAR1 (0.57) | POLBSMN1; SMN2SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2009760 | 0.68 | SIGMAR1 (0.56) | POLBSMN1; SMN2SIGMAR1MEN1KMT2A | |
| SCHEMBL28199271 | 0.67 | CA2 (0.38) | SIGMAR1KMT2AALDH1A1 | |
| SCHEMBL6632262 | 0.65 | SIGMAR1 (0.36) | SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698603-A | Thienopyrimidines, its preparation method, Pharmaceutical composition and its application | 厦门大学 | 2018-02-16 | — | — | CN | claimed |
| CN-107698603-A | Thienopyrimidines, its preparation method, Pharmaceutical composition and its application | 厦门大学 | 2018-02-16 | — | — | CN | disclosed |