Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 12/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 11/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 11/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28199273 | 0.83 | SIGMAR1 (0.36) | SIGMAR1GNAO1GNAI3GNAI1 | |
| SCHEMBL28509231 | 0.82 | SIGMAR1 (0.40) | SIGMAR1GNAO1GNAI3GNAI1FAAH | |
| SCHEMBL5731593 | 0.80 | SIGMAR1 (0.49) | SIGMAR1GNAO1GNAI3GNAI1FAAH | |
| SCHEMBL28856183 | 0.80 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL5521576 | 0.77 | MEN1 (0.41) | SIGMAR1 | |
| SCHEMBL19040775 | 0.76 | GNAO1 (0.43) | SIGMAR1GNAO1GNAI3GNAI1 | |
| SCHEMBL28199286 | 0.74 | POLB (0.41) | SIGMAR1 | |
| SCHEMBL6066343 | 0.73 | GNAI3 (0.38) | SIGMAR1GNAO1GNAI3GNAI1FAAH | |
| SCHEMBL2249240 | 0.72 | SIGMAR1 (0.42) | SIGMAR1GNAO1GNAI3GNAI1 | |
| SCHEMBL5369797 | 0.70 | TACR1 (0.55) | SIGMAR1GNAO1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100579957-C | Novel arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2010-01-13 | — | — | CN | disclosed |
| CN-1642906-A | Novel arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2005-07-20 | — | — | CN | disclosed |