SCHEMBL28856233

SCHEMBL28856233

NNP(=O)(O)Oc1cc(Cl)cc(Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HSPA5 P11021 1/20 0.33
CA1 P00915 2/20 0.32
CA14 Q9ULX7 1/20 0.32
INPPL1 O15357 1/20 0.31
INPP5B P32019 1/20 0.31
INPP5A Q14642 1/20 0.31
FDPS P14324 1/20 0.31
SCN9A Q15858 2/20 0.31
SCN2A Q99250 2/20 0.31
SCN3A Q9NY46 2/20 0.31
SCN10A Q9Y5Y9 2/20 0.31
SCN1A P35498 1/20 0.31
KCNH2 Q12809 1/20 0.31
SCN5A Q14524 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28200207 0.81 CA1 (0.40) ALDH1A1HPGDTSHRHSD17B10MAPT
SCHEMBL28856235 0.77 LMNA (0.39) ALDH1A1TSHRMAPTKDM4ECA14
SCHEMBL28200093 0.75 INPPL1 (0.33) ALDH1A1CA14INPPL1INPP5A
SCHEMBL28046072 0.72 LMNA (0.59) HPGDTSHRINPPL1INPP5BINPP5A
SCHEMBL28200081 0.69 ALDH1A1 (0.33) ALDH1A1HSD17B10KDM4ECA14INPPL1
Phosphoric Acid SCHEMBL20984216 0.68 HSPA5 (0.42) ALDH1A1HPGDTSHRHSD17B10MAPT
SCHEMBL28045406 0.68 MEN1 (0.57) ALDH1A1HPGDMAPTKDM4ECA1
SCHEMBL28856297 0.67 KDM4E (0.38) ALDH1A1HPGDTSHRHSD17B10MAPT
SCHEMBL28049339 0.67 CYP1A2 (0.53) ALDH1A1MAPT
Phosphoric Acid SCHEMBL20984848 0.65 MAPT (0.41) ALDH1A1HPGDTSHRHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed