Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 3/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 2/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.33 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 2/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896717 | 1.00 | SLC22A12 (0.36) | SLC22A12PPARAMAP3K14CNR2CDK8 | |
| SCHEMBL29896764 | 0.88 | ALDH1A1 (0.36) | SLC22A12PPARAPPOXATM | |
| SCHEMBL28856556 | 0.88 | ALDH1A1 (0.36) | SLC22A12PPARAPPOXATM | |
| SCHEMBL28856534 | 0.87 | PPARA (0.48) | SLC22A12PPARAMAP3K14 | |
| SCHEMBL29896734 | 0.87 | PPARA (0.48) | SLC22A12PPARAMAP3K14 | |
| SCHEMBL29896802 | 0.86 | SMN1; SMN2 (0.37) | SLC22A12PPARAPPOXATM | |
| SCHEMBL28856550 | 0.86 | SMN1; SMN2 (0.37) | SLC22A12PPARAPPOXATM | |
| SCHEMBL29896755 | 0.86 | AAK1 (0.39) | PPARAAAK1PPOX | |
| SCHEMBL28856498 | 0.86 | AAK1 (0.39) | PPARAAAK1PPOX | |
| SCHEMBL28856515 | 0.84 | SLC22A12 (0.43) | SLC22A12AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |