Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856556 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGDR2KDM4ENPSR1 | |
| SCHEMBL28856550 | 0.90 | SMN1; SMN2 (0.37) | ALDH1A1MAPTNPSR1ATMGAA | |
| SCHEMBL29896802 | 0.90 | SMN1; SMN2 (0.37) | ALDH1A1MAPTNPSR1ATMGAA | |
| SCHEMBL29896755 | 0.90 | AAK1 (0.39) | NMT1PPOXMEN1KMT2APPARA | |
| SCHEMBL28856498 | 0.90 | AAK1 (0.39) | NMT1PPOXMEN1KMT2APPARA | |
| SCHEMBL28856515 | 0.88 | SLC22A12 (0.43) | ALDH1A1PTGDR2SLC22A12TP53 | |
| SCHEMBL29896717 | 0.88 | SLC22A12 (0.36) | ATMSLC22A12PPOXPPARA | |
| SCHEMBL28856494 | 0.88 | SLC22A12 (0.36) | ATMSLC22A12PPOXPPARA | |
| SCHEMBL28856510 | 0.86 | PPARA (0.43) | PTGDR2SLC22A12HTR1AADRA1DADRA1A | |
| SCHEMBL29896814 | 0.86 | PPARA (0.43) | PTGDR2SLC22A12HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |