Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 12/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPOX | P50336 | 3/20 | 0.37 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896755 | 1.00 | AAK1 (0.39) | AAK1MEN1POLBKMT2APPOX | |
| SCHEMBL28856556 | 0.90 | ALDH1A1 (0.36) | MEN1KMT2APPOXNMT1PPARA | |
| SCHEMBL29896764 | 0.90 | ALDH1A1 (0.36) | MEN1KMT2APPOXNMT1PPARA | |
| SCHEMBL28856550 | 0.89 | SMN1; SMN2 (0.37) | MEN1KMT2APPOXPPARA | |
| SCHEMBL29896802 | 0.89 | SMN1; SMN2 (0.37) | MEN1KMT2APPOXPPARA | |
| SCHEMBL28856515 | 0.86 | SLC22A12 (0.43) | AAK1 | |
| SCHEMBL29896717 | 0.86 | SLC22A12 (0.36) | AAK1PPOXPPARA | |
| SCHEMBL28856494 | 0.86 | SLC22A12 (0.36) | AAK1PPOXPPARA | |
| SCHEMBL29896818 | 0.86 | PPARA (0.42) | AAK1PPARA | |
| SCHEMBL28856562 | 0.86 | PPARA (0.42) | AAK1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |