Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15882569 | 0.81 | TRPM8 (0.48) | TRPM8EPHX2EPHX1SIGMAR1DRD2 | |
| SCHEMBL29395374 | 0.73 | DRD2 (0.45) | TRPM8EPHX2TACR1TACR3GAA | |
| SCHEMBL30817420 | 0.73 | L3MBTL1 (0.38) | TRPM8GAAMAPTCYP3A4ALOX15 | |
| SCHEMBL9752016 | 0.72 | MAOA (0.41) | TRPM8GAAMAPTCYP3A4ALOX15 | |
| SCHEMBL3519499 | 0.72 | POLB (0.50) | MAPTALOX15MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27969301 | 0.72 | SIGMAR1 (0.43) | TRPM8EPHX2EPHX1GAASIGMAR1 | |
| SCHEMBL462820 | 0.71 | SIGMAR1 (0.45) | TRPM8EPHX2EPHX1GAASIGMAR1 | |
| SCHEMBL6467973 | 0.71 | SIGMAR1 (0.45) | TRPM8EPHX2EPHX1GAASIGMAR1 | |
| SCHEMBL3113866 | 0.71 | SIGMAR1 (0.45) | TRPM8EPHX2EPHX1GAASIGMAR1 | |
| SCHEMBL29392702 | 0.71 | SIGMAR1 (0.45) | TRPM8EPHX2EPHX1GAASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114150036-B | Continuous biphasic batch resolution process for preparing optically pure 6-fluoro-chroman-2-carboxylic acid | 华东理工大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-114150036-A | Continuous two-phase batch resolution process for preparing optically pure 6-fluoro-chroman-2-carboxylic acid | 华东理工大学 | 2022-03-08 | — | — | CN | disclosed |