Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27882553 | 0.85 | SLC1A1 (0.47) | SLC1A1MDM2PPARGPPARADAO | |
| SCHEMBL27882530 | 0.76 | ALDH1A1 (0.40) | MDM2PPARGPPARADAOMAOB | |
| SCHEMBL28188510 | 0.74 | LMNA (0.37) | MAOB | |
| SCHEMBL27562054 | 0.73 | CES2 (0.36) | MAOB | |
| SCHEMBL28065773 | 0.73 | TSHR (0.40) | SLC1A1PPARGPPARAMPOCNR1 | |
| SCHEMBL28837422 | 0.71 | GRIA2 (0.43) | — | |
| SCHEMBL8873187 | 0.70 | SLC1A1 (0.56) | SLC1A1MDM2PPARGPPARAHCAR2 | |
| SCHEMBL27723473 | 0.69 | MDM2 (0.47) | MDM2PPARGPPARAMAOB | |
| SCHEMBL27516632 | 0.69 | HDAC4 (0.46) | SLC1A1PPARGPPARA | |
| SCHEMBL27467459 | 0.69 | SLC1A1 (0.45) | SLC1A1MDM2PPARGPPARAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084138-A | Prepare the method and its pharmaceutical applications of optical voidness 2- (1- hydroxyl-alkyls)-chromen-4-one derivatives | 理森制药股份公司 | 2018-05-29 | — | — | CN | disclosed |
| CN-104507922-B | Novel method for producing optically pure and optionally substituted 2- (1-hydroxy-alkyl) -chromen-4-one derivatives and the use thereof for producing medicaments | 理森制药股份公司 | 2018-02-09 | — | — | CN | disclosed |