Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 6/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971349 | 0.92 | IDE (0.40) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL19971346 | 0.89 | IDE (0.41) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL19971352 | 0.85 | PDE4A (0.42) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL28068051 | 0.85 | IDE (0.41) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL19971359 | 0.83 | HTR6 (0.42) | IDEHTR6CHRNB4CHRNA3 | |
| SCHEMBL28857516 | 0.81 | IDE (0.41) | IDEHTR6 | |
| SCHEMBL16619302 | 0.81 | HTR6 (0.44) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL2472672 | 0.80 | NAMPT (0.43) | IDENAMPTHDAC1TSHRHTT | |
| SCHEMBL19971356 | 0.79 | IDE (0.37) | IDENAMPTPDE4APDE4BPDE4C | |
| SCHEMBL16626633 | 0.78 | HTR6 (0.38) | IDEPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |