Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.31 |
| ▸ | RELA | Q04206 | 3/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014569 | 0.86 | BCHE (0.47) | BCHEAKT1ALDH1A1MAPTNFKB1 | |
| Alanine SCHEMBL4360421 | 0.69 | ALDH1A1 (0.38) | SLC7A5ALDH1A1MAPTNFKB1 | |
| Alanine SCHEMBL27608134 | 0.67 | ALDH1A1 (0.37) | SLC7A5ALDH1A1MAPTNFKB1GRIN2B | |
| Benzoquinone SCHEMBL28732321 | 0.66 | ALDH1A1 (0.42) | BCHESLC7A5ALDH1A1MAPK1 | |
| Benzoquinone SCHEMBL12500012 | 0.66 | ALDH1A1 (0.42) | BCHESLC7A5ALDH1A1MAPK1 | |
| Benzene SCHEMBL28152515 | 0.65 | CYP3A4 (0.45) | SLC7A5ALDH1A1MAPTNFKB1GRIN2B | |
| Alanine SCHEMBL11442545 | 0.65 | — | — | |
| SCHEMBL3630207 | 0.64 | P2RX4 (0.48) | BCHETSHRHTTALDH1A1MAPT | |
| SCHEMBL320438 | 0.64 | P2RX4 (0.48) | BCHETSHRHTTALDH1A1MAPT | |
| SCHEMBL7814662 | 0.64 | NOS1 (0.37) | SLC7A5ALDH1A1MAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108025084-A | Antibody Drug Conjugates (ADC) and antibody prodrug conjugates (APDC) with enzyme cleavable groups | 拜耳医药股份有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107921146-A | Spindle drives the antibody drug conjugate (ADC) of albumen (KSP) inhibitor and the antibody of anti-CD123 | 拜耳医药股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107921145-A | The antibody drug conjugate of KSP inhibitor and anti-TWEAKR antibody（ADC） | 拜耳医药股份有限公司 | 2018-04-17 | — | — | CN | disclosed |