Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GALR3 | O60755 | 3/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176723 | 0.76 | KDM4E (0.50) | MAPK1ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL353890 | 0.76 | SMN1; SMN2 (0.63) | HTTMAPK1TNFTSHRALDH1A1 | |
| SCHEMBL66294 | 0.76 | SMN1; SMN2 (0.63) | HTTMAPK1TNFKMT2ASMN1; SMN2 | |
| SCHEMBL10980166 | 0.75 | NLRP3 (0.42) | HTTALDH1A1KMT2ALMNARAB9A | |
| SCHEMBL18347137 | 0.74 | HTT (0.55) | HTTMAPK1TNFTSHRALDH1A1 | |
| SCHEMBL8422526 | 0.74 | HTT (0.55) | HTTMAPK1TNFTSHRALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL19182582 | 0.74 | SMN1; SMN2 (0.61) | HTTMAPK1TNFTSHRALDH1A1 | |
| Bromide SCHEMBL5318089 | 0.74 | SMN1; SMN2 (0.61) | HTTMAPK1TNFTSHRALDH1A1 | |
| SCHEMBL20143511 | 0.74 | HTT (0.55) | HTTMAPK1TNFTSHRALDH1A1 | |
| SCHEMBL13839193 | 0.74 | HTT (0.55) | HTTMAPK1TNFTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820825-B2 | N-substituted-azacyclylamines as histamine-3 antagonists | WYETH LLC (US) | 2010-10-26 | — | — | US | disclosed |
| US-20090167156-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20090167156-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20070219240-A1 | N-substituted-azacyclylamines as histamine-3 antagonists | WYETH (US) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219240-A1 | N-substituted-azacyclylamines as histamine-3 antagonists | HNMT, HRH4, HRH3 | HTT 396/4885MAPK1 2465/4885TNF 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.