Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.40 |
| ▸ | THRA | P10827 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | FOXO1 | Q12778 | 2/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21496000 | 0.82 | THRB (0.50) | THRBTHRAFOXO1GSTP1HRH3 | |
| SCHEMBL23293901 | 0.79 | ALDH1A1 (0.43) | THRBTHRAKDM4EFOXO1GSTP1 | |
| SCHEMBL10428604 | 0.78 | THRB (0.39) | THRBTHRAKDM4EMEN1KMT2A | |
| SCHEMBL28237336 | 0.77 | THRB (0.46) | THRBMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11865899 | 0.74 | THRB (0.40) | THRBTHRAKDM4EMEN1KMT2A | |
| SCHEMBL5590860 | 0.72 | THRB (0.39) | THRBTHRAKDM4EMEN1KMT2A | |
| SCHEMBL11865894 | 0.72 | HCAR2 (0.49) | THRBTHRAKDM4EMEN1KMT2A | |
| SCHEMBL28269392 | 0.71 | TDP1 (0.43) | MEN1KMT2AALDH1A1TDP1HCAR2 | |
| SCHEMBL28419815 | 0.69 | GSTP1 (0.38) | THRBTHRAGSTP1HCAR2 | |
| SCHEMBL28796088 | 0.69 | THRB (0.41) | THRBTHRAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108136745-A | Stack membrane | 东丽株式会社 | 2018-06-08 | — | — | CN | disclosed |