Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.39 |
| ▸ | THRA | P10827 | 8/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364273 | 0.83 | LMNA (0.45) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL28796088 | 0.78 | THRB (0.41) | THRBTHRAHRH3MEN1KMT2A | |
| SCHEMBL4441223 | 0.78 | THRB (0.43) | THRBTHRAHRH3MEN1KMT2A | |
| SCHEMBL10428604 | 0.76 | THRB (0.39) | THRBTHRAHRH3MEN1KMT2A | |
| SCHEMBL2270833 | 0.75 | ALDH1A1 (0.49) | THRBTHRAHRH3MEN1KMT2A | |
| SCHEMBL5590861 | 0.74 | HRH3 (0.49) | THRBTHRAHRH3MEN1KMT2A | |
| SCHEMBL12370730 | 0.73 | ALDH1A1 (0.47) | THRBTHRAHRH3MEN1KMT2A | |
| SCHEMBL28860686 | 0.72 | THRB (0.40) | THRBTHRAHRH3MEN1KMT2A | |
| SCHEMBL10596654 | 0.72 | THRB (0.39) | THRBTHRAHRH3MEN1KMT2A | |
| SCHEMBL12370716 | 0.71 | ALDH1A1 (0.35) | THRBTHRAHRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765263-A1 | DENTAL COMPOSITION CONTAINING SI-H FUNCTIONAL CARBOSILANE COMPONENTS | 3M Espe AG (DE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005366-A1 | DENTAL COMPOSITION CONTAINING SI-H FUNCTIONAL CARBOSILANE COMPONENTS | 3M ESPE AG (DE) | 2006-01-19 | — | — | WO | disclosed |