Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 2/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14143718 | 0.86 | POLB (0.38) | POLBGAATSPOCA12CA1 | |
| SCHEMBL19334460 | 0.81 | ALDH1A1 (0.47) | CA12CA1CA2CA9RXRA | |
| SCHEMBL341742 | 0.81 | PLA2G2A (0.47) | POLBGAATSPOTPMTKEAP1 | |
| SCHEMBL15122362 | 0.81 | KEAP1 (0.43) | POLBTPMTKEAP1NFE2L2NPSR1 | |
| SCHEMBL3348892 | 0.79 | KEAP1 (0.54) | GAACA12CA1CA2CA9 | |
| SCHEMBL9795610 | 0.78 | POLB (0.42) | POLBGAATSPOTPMTKEAP1 | |
| SCHEMBL26558157 | 0.76 | BLM (0.44) | POLBGAATSPOTPMTKEAP1 | |
| SCHEMBL20322823 | 0.75 | SMN1; SMN2 (0.45) | POLBCA12CA1CA2CA9 | |
| SCHEMBL28486134 | 0.74 | HDAC1 (0.41) | POLBGAACA1CA2 | |
| SCHEMBL196635 | 0.74 | KMT2A (0.49) | POLBCA12CA2CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203438-A | Condensed imidazole compound with indole amine 2,3-dioxygenase inhibitory activity | 深圳微芯生物科技股份有限公司 | 2018-06-26 | — | — | CN | disclosed |