SCHEMBL3348892

SCHEMBL3348892

Cc1ccc(N(C)CC(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.54
NFE2L2 Q16236 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
RAB9A P51151 1/20 0.44
PPARG P37231 1/20 0.43
KMT2A Q03164 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11560187 0.85 ALDH1A1 (0.46) KEAP1NFE2L2SMN1; SMN2ALDH1A1TSHR
SCHEMBL797850 0.83 CA2 (0.43) KEAP1NFE2L2ALDH1A1CA12CA1
SCHEMBL196635 0.83 KMT2A (0.49) SMN1; SMN2ALDH1A1TSHRRAB9AKMT2A
SCHEMBL8541381 0.82 ALDH1A1 (0.45) KEAP1NFE2L2SMN1; SMN2ALDH1A1TSHR
SCHEMBL3349309 0.82 MAPT (0.41) KEAP1NFE2L2SMN1; SMN2ALDH1A1RAB9A
SCHEMBL5726224 0.82 TDP1 (0.46) KEAP1NFE2L2SMN1; SMN2ALDH1A1TSHR
SCHEMBL10906215 0.82 ALDH1A1 (0.57) ALDH1A1RAB9AKMT2ACA12CA1
SCHEMBL14364107 0.82 SLC6A9 (0.40) KEAP1NFE2L2SMN1; SMN2ALDH1A1CA12
SCHEMBL9632043 0.82 TPMT (0.40) KEAP1NFE2L2ALDH1A1KMT2ACA12
SCHEMBL3763384 0.82 NPC1 (0.50) SMN1; SMN2ALDH1A1TSHRRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153236-A Comprising an N-aryl-alpha-amino acid and a photosensitizer such as a thixoanthone, isoalloxazine or coumarine; high sensitivity to UV and visible light; storage stability; photoresists; relief images HITACHI CHEMICAL CO., LTD. (JP) 1992-10-06 US claimed
CN-120077329-A Photosensitive resin composition, photosensitive resin laminate, and method for forming resist pattern 旭化成株式会社 2025-05-30 CN disclosed
CN-118159908-A Photosensitive element and method for forming resist pattern 旭化成株式会社 2024-06-07 CN disclosed
WO-2024085254-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN MULTILAYER BODY, AND METHOD FOR FORMING RESIST PATTERN 旭化成株式会社 2024-04-25 WO disclosed
WO-2023074325-A1 PHOTOSENSITIVE ELEMENT, AND METHOD FOR FORMING RESIST PATTERN 旭化成株式会社 2023-05-04 WO disclosed
CN-107849417-B Adhesive composition, cured product, semiconductor device, and method for producing same 昭和电工材料株式会社 2021-06-29 CN disclosed
CN-105934478-B Resin composition, method for manufacturing semiconductor device using resin composition, and solid-state imaging element 日立化成株式会社 2020-01-14 CN disclosed
EP-2951173-B1 NOVEL SUBSTITUTED CONDENSED PYRIMIDINE COMPOUNDS GRUENENTHAL GMBH (DE) 2017-05-17 EP disclosed
US-9505724-B2 4-amino substituted condensed pyrimidine compounds as PDE4 inhibitors Grünenthal GmbH (DE) 2016-11-29 US disclosed
US-20150353507-A1 4-AMINO SUBSTITUTED CONDENSED PYRIMIDINE COMPOUNDS AS PDE4 INHIBITORS Grünenthal GmbH (DE) 2015-12-10 US disclosed
US-20050037934-A1 Hair cosmetic, aminocarboxylic acid amide and method for producing the same KAO CORPORATION (JP) 2005-02-17 US disclosed
US-20030035784-A1 Hair cosmetic, aminocarboxylic acid amide and method for producing the same KAO CORPORATION (JP) 2003-02-20 US disclosed
EP-1238966-A2 Hair cosmetic, aminocarboxylic acid amide and method for producing the same KAO CORPORATION (JP) 2002-09-11 EP disclosed
US-5789610-A Adhesion-promoting agents incorporating polyvalent cations AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1998-08-04 US disclosed
US-5401783-A Adhesion-promoting agents incorporating polyvalent cations AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1995-03-28 US disclosed
US-5270351-A Adhesion-promoting agents incorporating polyvalent cations AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1993-12-14 US disclosed
US-5153236-A Comprising an N-aryl-alpha-amino acid and a photosensitizer such as a thixoanthone, isoalloxazine or coumarine; high sensitivity to UV and visible light; storage stability; photoresists; relief images HITACHI CHEMICAL CO., LTD. (JP) 1992-10-06 US disclosed
EP-0295044-B1 PHOTOINITIATOR AND PHOTOPOLYMERIZABLE COMPOSITION USING THE SAME Hitachi Chemical Co., Ltd. (JP) 1992-04-22 EP disclosed
US-4987057-A HIGH SENSITIVITY TO VISIBLE LIGHT RAYS HITACHI CHEMICAL CO., LTD. (JP) 1991-01-22 US disclosed
EP-0295044-A2 Photoinitiator and photopolymerizable composition using the same Hitachi Chemical Co., Ltd. (JP) 1988-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030035784-A1 Hair cosmetic, aminocarboxylic acid amide and method for producing the same QARS1, ACMSD, H1-5 KEAP1 3463/4885NFE2L2 3147/4885SMN1; SMN2 4802/4885
US-20050037934-A1 Hair cosmetic, aminocarboxylic acid amide and method for producing the same ACMSD, H1-0, H1-2 KEAP1 4033/4885NFE2L2 3836/4885SMN1; SMN2 4639/4885
US-20150353507-A1 4-AMINO SUBSTITUTED CONDENSED PYRIMIDINE COMPOUNDS AS PDE4 INHIBITORS PDE4A, PDE4B, PDE12 KEAP1 2115/4885NFE2L2 1604/4885SMN1; SMN2 2859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.