Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15571300 | 0.83 | LMNA (0.55) | PIK3CAHTTHSD17B10ALDH1A1MAPT | |
| SCHEMBL15570147 | 0.77 | SMN1; SMN2 (0.55) | HTTHSD17B10ALDH1A1MAPTNPC1 | |
| SCHEMBL27497441 | 0.76 | HTR1A (0.70) | HSD17B10ALDH1A1GAAUSP2MEN1 | |
| SCHEMBL4027686 | 0.75 | CHKA (0.57) | HTTHSD17B10ALDH1A1GAAMAPT | |
| SCHEMBL27741416 | 0.74 | ALDH1A1 (0.76) | HTTHSD17B10ALDH1A1GAAMAPT | |
| SCHEMBL30469317 | 0.74 | ADRA2C (0.66) | HTTHSD17B10ALDH1A1GAAMAPT | |
| SCHEMBL1397693 | 0.74 | ADRA2C (0.66) | HTTHSD17B10ALDH1A1GAAMAPT | |
| SCHEMBL15928733 | 0.74 | ADRA2C (0.66) | HTTHSD17B10ALDH1A1GAAMAPT | |
| SCHEMBL29378385 | 0.74 | ADRA2C (0.66) | HTTHSD17B10ALDH1A1GAAMAPT | |
| Fluoride SCHEMBL27569609 | 0.74 | CHKA (0.56) | HTTHSD17B10ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283443-B | Hete rocyclic derivatives and application thereof | 株式会社C&C新药研究所 | 2018-08-17 | — | — | CN | disclosed |