Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403558 | 0.79 | TSHR (0.36) | SLC1A2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21014820 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL2036449 | 0.72 | KMT2A (0.43) | ALDH1A1SLC1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL21243694 | 0.70 | HCAR2 (0.43) | ALDH1A1SLC1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL9841192 | 0.69 | TSHR (0.32) | — | |
| SCHEMBL6472544 | 0.69 | — | — | |
| SCHEMBL2886829 | 0.69 | MGLL (0.31) | — | |
| SCHEMBL7351000 | 0.68 | MGAM (0.38) | ALDH1A1PKMSLC1A2CHRM2CHRM4 | |
| SCHEMBL5198395 | 0.68 | — | — | |
| SCHEMBL406639 | 0.68 | CHRM2 (0.34) | ALDH1A1PKMSLC1A2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757033-B1 | Vinyl carbonate and vinyl carbamate monomers for a contact lens material | BAUSCH & LOMB (US) | 1999-03-03 | — | — | EP | claimed |
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | claimed |
| EP-0396364-A2 | Novel vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1990-11-07 | — | — | EP | claimed |
| US-7745564-B2 | System for synthesis of device forming monomers | BAUSCH & LOMB INCORPORATED (US) | 2010-06-29 | — | — | US | disclosed |
| WO-2007002343-A2 | NOVEL SYSTEM FOR SYNTHESIS OF DEVICE FORMING MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060293476-A1 | Novel system for synthesis of device forming monomers | PRECISION DERMATOLOGY, INC. | 2006-12-28 | — | — | US | disclosed |
| US-6166236-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0757033-B1 | Vinyl carbonate and vinyl carbamate monomers for a contact lens material | BAUSCH & LOMB (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5610252-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0757033-A2 | Vinyl carbonate and vinyl carbamate monomers for a contact lens material | BAUSCH & LOMB INCORPORATED (US) | 1997-02-05 | — | — | EP | disclosed |
| US-5070215-A | Gas permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0396364-A2 | Novel vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1990-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293476-A1 | Novel system for synthesis of device forming monomers | ILK, ALKBH3, FTO | ALDH1A1 2198/4885PKM 1307/4885SLC1A2 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.