Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 4/20 | 0.36 |
| ▸ | MMP9 | P14780 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865195 | 0.69 | ALDH1A1 (0.44) | ALDH1A1TP53MMP8MMP9NPSR1 | |
| SCHEMBL6221243 | 0.69 | SMN1; SMN2 (0.34) | MMP9MMP2LMNA | |
| SCHEMBL12013779 | 0.67 | TP53 (0.57) | ALDH1A1TP53MMP8MMP9MMP2 | |
| SCHEMBL6690127 | 0.67 | POLB (0.31) | TP53POLB | |
| SCHEMBL2473210 | 0.66 | SMN1; SMN2 (0.32) | MMP9MMP2LMNA | |
| SCHEMBL1583554 | 0.66 | SMN1; SMN2 (0.32) | MMP9MMP2LMNA | |
| SCHEMBL3546319 | 0.65 | ALDH1A1 (0.41) | ALDH1A1MMP8MMP9TSHRGABRA5 | |
| SCHEMBL7645981 | 0.65 | LMNA (0.64) | ALDH1A1TP53MMP8MMP9MMP2 | |
| SCHEMBL12189561 | 0.64 | CRBN (0.33) | — | |
| SCHEMBL21990716 | 0.64 | ATAD2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |