Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838102 | 0.86 | PREP (0.37) | USP2SMN1; SMN2PREPALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28241841 | 0.85 | PREP (0.36) | USP2SMN1; SMN2PREPALDH1A1LMNA | |
| SCHEMBL28856336 | 0.85 | CHRM2 (0.38) | USP2SMN1; SMN2PREPALDH1A1LMNA | |
| Piperazine SCHEMBL28059508 | 0.79 | PREP (0.33) | USP2SMN1; SMN2PREPALDH1A1LMNA | |
| Pyrrole SCHEMBL28865869 | 0.77 | GPR119 (0.32) | USP2SMN1; SMN2PREP | |
| SCHEMBL28854569 | 0.74 | NR1H2 (0.34) | USP2SMN1; SMN2PREP | |
| SCHEMBL4540593 | 0.70 | — | — | |
| SCHEMBL3797610 | 0.70 | — | — | |
| SCHEMBL6034344 | 0.69 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4774116 | 0.69 | TSHR (0.34) | SMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519273-A1 | KRAS G12D PROTEOLYSIS TARGETING CHIMERAS | Paq Therapeutics Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215906-A1 | KRAS G12D PROTEOLYSIS TARGETING CHIMERAS | HANGZHOU JIJING PHARMACEUTICALTECHNOLOGY LIMITED (CN) | 2023-11-09 | — | — | WO | disclosed |