Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220923 | 0.83 | PLA2G2A (0.51) | L3MBTL1SMN1; SMN2LMNAPLA2G2AMAPT | |
| SCHEMBL1010680 | 0.81 | LMNA (0.64) | L3MBTL1SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL1029593 | 0.81 | PDE4A (0.45) | L3MBTL1SMN1; SMN2LMNAMAPTHSD17B10 | |
| SCHEMBL1032325 | 0.80 | CA12 (0.50) | L3MBTL1SMN1; SMN2LMNACA12CA1 | |
| SCHEMBL505777 | 0.76 | CA1 (0.50) | L3MBTL1SMN1; SMN2LMNAMAPTHSD17B10 | |
| SCHEMBL26046334 | 0.76 | LMNA (0.47) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL26046399 | 0.76 | ALDH1A1 (0.49) | L3MBTL1LMNANR3C2CA12CA1 | |
| SCHEMBL431188 | 0.75 | GABRA1 (0.45) | PLA2G2AICMTKDM4ECA2 | |
| SCHEMBL9003109 | 0.75 | SMN1; SMN2 (0.57) | L3MBTL1SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL9003104 | 0.75 | SMN1; SMN2 (0.57) | L3MBTL1SMN1; SMN2LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884044-A | PIPERIDINE DERIVATIVE | 大塚制药株式会社 | 2018-11-23 | — | — | CN | disclosed |