Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16268913 | 0.82 | HTR1A (0.51) | SLC6A4SLC6A2SLC6A3TDP1ALOX15 | |
| SCHEMBL1341376 | 0.79 | MEN1 (0.52) | SLC6A4SLC6A2SLC6A3ALDH1A1CYP3A4 | |
| SCHEMBL30567146 | 0.79 | MEN1 (0.52) | SLC6A4SLC6A2SLC6A3ALDH1A1CYP3A4 | |
| SCHEMBL810752 | 0.77 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3TDP1NPC1 | |
| SCHEMBL28867147 | 0.76 | G6PD (0.47) | SLC6A4SLC6A2SLC6A3TDP1ALDH1A1 | |
| SCHEMBL29773377 | 0.75 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3TDP1NPC1 | |
| SCHEMBL14723181 | 0.75 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3TDP1NPC1 | |
| SCHEMBL30338359 | 0.75 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3TDP1NPC1 | |
| SCHEMBL4130402 | 0.75 | ALOX15 (0.48) | SLC6A4SLC6A2SLC6A3TDP1NPC1 | |
| SCHEMBL3195118 | 0.74 | KDM4E (0.71) | SLC6A4SLC6A2SLC6A3TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338605-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2012-12-25 | — | — | US | disclosed |
| CN-102702194-A | Anti-viral compounds | ABBOTT LAB | 2012-10-03 | — | — | CN | disclosed |
| US-20100256139-A1 | Anti-Viral Compounds | ABBOTT LABORATORIES (US) | 2010-10-07 | — | — | US | disclosed |
| EP-1979349-B1 | ANTI-VIRAL COMPOUNDS | ABBOTT LAB (US) | 2010-07-28 | — | — | EP | disclosed |
| US-7763731-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2010-07-27 | — | — | US | disclosed |
| CN-101384592-A | Antiviral compounds | ABBOTT LAB (US) | 2009-03-11 | — | — | CN | disclosed |
| EP-1979349-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| US-20070232645-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. | 2007-10-04 | — | — | US | disclosed |
| WO-2007076035-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232645-A1 | ANTI-VIRAL COMPOUNDS | HAVCR2, MAVS, EIF2AK2 | SLC6A4 4037/4885SLC6A2 4033/4885SLC6A3 3970/4885 |
| US-20100256139-A1 | Anti-Viral Compounds | HAVCR2, MAVS, EIF2AK2 | SLC6A4 4037/4885SLC6A2 4033/4885SLC6A3 3970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.