SCHEMBL28867148

SCHEMBL28867148

COC(=O)Nc1nc2ccc(S(=O)(=O)c3ccccc3)cc2[nH]1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 8/20 0.65
CYP1A2 P05177 6/20 0.65
HIF1A Q16665 5/20 0.65
ALDH1A1 P00352 3/20 0.65
KDR P35968 3/20 0.65
ABL1 P00519 2/20 0.65
CYP2C9 P11712 2/20 0.65
HTT P42858 2/20 0.65
ABCC4 O15439 1/20 0.65
USP2 O75604 1/20 0.65
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
NR1I2 O75469 1/20 0.64
MAPK14 Q16539 1/20 0.64
HPGD P15428 3/20 0.63
ADORA2A P29274 2/20 0.63
KDM4E B2RXH2 1/20 0.63
CYP3A4 P08684 1/20 0.63
HSD17B10 Q99714 1/20 0.63
ACR P10323 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10627091 0.90 LMNA (0.56) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL11449416 0.86 TUBB4A (0.63) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL4386009 0.85 ACR (0.63) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL11449263 0.82 TUBB4A (0.56) LMNACYP1A2HIF1AALDH1A1KDR
Carbendazim SCHEMBL2692102 0.81 ALDH1A1 (0.57) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL11449686 0.81 TUBB4A (0.55) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL28144116 0.81 LMNA (0.65) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL11467174 0.80 TUBB4A (0.54) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL11448682 0.80 TUBB4A (0.64) LMNACYP1A2HIF1AALDH1A1KDR
Oxfendazole SCHEMBL9818561 0.80 LMNA (0.64) LMNACYP1A2HIF1AALDH1A1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117825570-A Method for simultaneously detecting imidazole drugs and metabolic residues thereof in food 重庆市计量质量检测研究院 2024-04-05 CN disclosed
CN-108828110-B Method for determining residual quantity of benzimidazole drugs in chicken fat 广东出入境检验检疫局检验检疫技术中心 2021-09-21 CN disclosed
CN-109001334-B Method for measuring residual quantity of benzimidazole drugs in chicken tissues 广东出入境检验检疫局检验检疫技术中心 2021-04-27 CN disclosed
CN-109001334-A The measuring method of benzimidazoles residues residual quantity in a kind of chicken tissues 广东出入境检验检疫局检验检疫技术中心 2018-12-14 CN disclosed